1988 Volume 40 Issue 4 Pages 456-463
We studied the change of left ventricular ejection fraction (LVEF) and infarcted and noninfarcted regional ejection fraction (REF) during bicycle ergometer exercise as an index of cardiac performance in 30 patients with myocardial infarction (MI) at 1 month after the onset of MI using RI angiocardiography. LVEF, I-REF and N-REF were reestimated at 1 year after MI in 23 patients.
LVEF in cresed significantly from 42±13% to 45±12% during exercise, N-REF also incresed from 47±14 to 52±16% during exercise, but I-REF did not change during exercise at 1 month after MI. However, LVEF, N-REF and I-REF at rest increased significantly from 1 month to 1 year. % change of LVEF during exercise at 1 month after MI correlated well with %change of resting LVEF from 1 month to 1 year (r= 0.65, P<0.05). Moreover, % change of N-REF during exercise at 1 month after MI showed more excellent correlation with %change of N-REF from 1 month to 1 year than % change of LVEF during exercise at 1month (r =0.72, P<0.01).
Thus, N-REF is a majo r determinant of the change of cardiac performance during exercise at 1 month after MI. The change of cardiac performance at 1 year after MI could be predicted by evaluating the change of N-REF during exercise at 1 month after MI.
