Hemorheology and Microcirculation in Chronic Renal Failure
What is the Optimum Hematocrit Value after Recombinant Human Erythropoietin T h erapy ?
1992 Volume 44 Issue 4 Pages 314-330
Details
1992 Volume 44 Issue 4 Pages 314-330
21 CRF patients undergone hemodialysis were se rved. On dialysis days, they were administered rHuEPO in does of 1,500 and/or 3,000 units. When the Ht values reached 25%,30%,35% (at posthemodialysis), whole blood viscosities at high shear rate (94.5sec-1) and at low shear rate (0.376sec-1), plasma viscosities at high shear rate were measured before and after hemodialysis. The passage time of 40% red cell suspension (for RBC deformability) was also measured. Internal diameters (ID), blood flow velocities (FVE), blood flow volumes (FVO) and intravascular erythrocyte aggregations (IEA) were analyzed in same microvenules on the human bulbar conjunctiva by using IVVMS and Distance Meter Method.
