Abstract
OASIS ® wound matrix is a natural extracellular matrix originating from the tunica submucosa of the porcine small intestine and functions as a biological scaffold facilitating wound closure of difficult-to-heal wounds. We report four cases of difficult-to-heal wounds treated by OASIS ®. Case 1: A 53-year-old man who works in a prolonged dependent leg position underwent stripping operations. Although careful vein stripping was performed, his wounds remained unhealed for 3-4 years. Case 2: An 85-year-old woman with previous endovascular laser treatments for venous insufficiency had a recurrent leg ulcer. In both cases, once OASIS ® was applied, the wounds fully healed in one to three months. Case 3: A 90-year-old woman had recurrent venous leg ulcers. During OASIS ® treatment, the wounds became infected and OASIS ® was discontinued. Case 4: A 76-year-old man with a past medical history of vein stripping, end-stage renal failure and critical limb ischemia had non-healing foot ulcers. After revascularization, negative wound pressure treatment by OASIS ® was applied to the foot ulcers. The wounds quickly healed. Three of our cases demonstrated the effectiveness of OASIS ® for venous and critical limb ischemic foot ulcers.
