Abstract
Objective: To assess prognostic factors associated with major adverse event (MAE) after endovascular therapy (EVT) for hemodialysis patients with critical limb ischemia (CLI). Method: Between September 2009 and October 2010, 72 hemodialysis patients with CLI (Rutherford 5 and 6: 79%) were studied. Definition of MAE was included major amputation or death, and the independent predictors of MAE were analyzed. Results: Overall MAE was observed in 24% (17/72). In the patients with MAE group patients with spending longer time before they consulted cardiovascular specialist (with MAE: 243±245 days vs without MAE: 114±112 days, P=0.014), lower BMI (with MAE group: 20±2 vs without MAE: 22±3, P=0.01) and higher CRP level (MAE: 4.4±5.1 mg/dl vs without MAE: 1.5±2.8 mg/dl, P=0.003) were more frequently observed. Conclusion: Time to visit vascular specialist, BMI and CRP level were predictors of MAE. Sustained limb salvage and clinical success can be achieved with an active surveillance program, multidiscipline team care, and prompt assisted EVT during long-term follow-up.
