Abstract
Objective: The purpose of this study was to evaluate the efficacy of infrainguinal arterial reconstruction for critical limb ischemia in patients with end-stage renal disease (ESRD). Materials and Methods: From April, 2007 to March, 2011, 126 limbs in 103 patients with ESRD and 84 limbs in 75 patients with functioning kidneys underwent infrainguinal arterial reconstruction for limb salvage. The prevalence of coronary arterial disease was higher in the ESRD group (p<0.01). Results: Operative mortality and 2-year survival rate were significantly poorer in patients with ESRD (11 vs 2%; p<0.01, and 44 vs 70%, p<0.01, respectively). Most causes of death were related to atherosclerosis or infectious diseases. Although there was no significant difference in 2-year limb salvage rate between ESRD and non-ESRD groups (86 vs 91%), limb loss occurred as a result of uncontrolled infection in five cases in the ESRD group and one case in non-ESRF group. Conclusions: Operative mortality and patient survival rate were significantly poorer in the ESRD group. Preoperative full evaluation of cardiovascular system, appropriate treatment for wound infection, and careful follow-up for comorbid diseases may be needed in these patients.
