Abstract
In the management of chronic wound infection topical antimicrobial therapy is required to reduce wound bacterial load. Topical agents containing silver or iodine are useful because they have a broad spectrum of antibacterial activity and the development of bacterial resistance is unusual. The use of topical antibiotic ointment is not generally recommended to minimize the risk of the induction of resistance. It is also important to understand ointment bases to select appropriate topical agents matching the wound conditions.
