Abstract
In this study, patients with heart diseases were
classified into 2 groups: Warfarin user and
Warfarin non-user, and six salivary components
were determined to assess intraoral pathologic
conditions. Groups of healthy subjects and
patients with periodontal disease without receiving
any medication were set as control groups, and
they were compared with those of the 2 groups
with heart diseases. In patients with heart diseases
in both the groups, albumin (ALB) level was found
to be significantly higher compared to that in the
control groups, and it was significantly higher in
the patient group receiving Warfarin user and
Warfarin non-user compared to that in the patient
group with periodontal disease. C-reactive protein
(CRP) levels were found to be higher in both the
groups with heart diseases than those in the
healthy group. Correlations between various salivary
components and the clinical parameters
were examined, showing significant correlations
between ALB and gingival index (GI) and clinical
attachment level (CAL), and between alanine
aminotransferase (ALT) and GI, probing depth
(PlI), bleeding on probing (BOP) and CAL.
Significant correlations were also found between
creatine kinase (CK) and PlI, GI and BOP. Thus, it
was suggested that ALB and CRP might serve as
the markers of intraoral pathologic conditions,
and CK and ALT might serve as those alternative to
GI.
