The Journal of Medical Investigation
Online ISSN : 1349-6867
Print ISSN : 1343-1420
ISSN-L : 1343-1420
The ratio of contrast medium volume to estimated glomerular filtration rate as a predictor of contrast‐induced nephropathy after endovascular aortic repair
Yohei KawataniHirotsugu KurobeYoshitsugu NakamuraTakaki HoriTetsuya Kitagawa
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2018 Volume 65 Issue 1.2 Pages 116-121

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Abstract

Objective:This study aimed to determine the perioperative predictors of contrast medium‐induced nephropathy (CIN) after endovascular aortic repair (EVAR). Materials and Methods:The data of 203 consecutive patients who underwent elective EVAR for thoracic and abdominal aortic aneurysm between January 2014 and September 2014 were retrospectively analyzed. CIN was defined according to the diagnostic criteria of the European Society of Urogenital Radiology. Results:Fourteen patients (6.9%) developed CIN after EVAR. Contrast medium volume (CV), preoperative serum creatinine, estimated glomerular filtration rate (eGFR), and the CV/eGFR ratio were significantly related with CIN development after EVAR. The CV/eGFR ratio was significantly higher in patients with CIN than those without CIN. Receiver operator characteristic curve analysis showed that the area under the curve of the CV/eGFR ratio was 0.782, indicating that it was the most important predictor. The appropriate CV/eGFR ratio cutoff was 1.62. Sensitivity and specificity were 85.7% and 65.6%, respectively. Conclusions:The CV/eGFR ratio was a useful predictor of contrast medium‐induced nephropathy after EVAR. It is possible that the score can be used in patients when managing the EVAR techniques and contrast medium volume. J. Med. Invest. 65:116‐121, February, 2018

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© 2018 by The University of Tokushima Faculty of Medicine
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