2026 Volume 73 Issue 3.4 Pages 525-527
Ehlers–Danlos syndrome has 13 subtypes and is associated with severe complications during pregnancy. However, there have been no previous reports of pregnancy and perinatal outcomes of cases of periodontal Ehlers–Danlos syndrome (pEDS). To the best of our knowledge, we report the first case of pEDS in pregnancy with successful delivery. A 34-year-old patient who was diagnosed with pEDS underwent genetic counseling. The patient and her partner understood that there were many unknown risks associated with pregnancy and childbirth but still wished to undergo infertility treatment. Pregnancy was achieved through assisted reproductive technology. She was hospitalized for preterm labor from 28 to 36 weeks of pregnancy. At 38 weeks, vacuum extraction was performed because of fetal distress. The postpartum course was uneventful, and there were no major problems with wound healing after delivery. This case could serve as a reference for women with pEDS who wish to become pregnant. J. Med. Invest. 73 : 525-527, August, 2026
