Abstract
We investigated the indication of primary ICSI. In 639 cycles (356 cases) of conventional IVF, we examined the fertilization rate and pregnancy rate upon following items. Those were appearance and concentration of sperm, female age, and picked up oocyte. In the study of correlation between sperm concentration and rate of fertilization or pregnancy, the cases of sperm concentration less than 10 × 106/ml were fertilized only 13.3% (18/135) or no cases were got pregnant (0/21). But in the study of correlation between sperm motility rate and rate of fertilization or pregnancy, even in cases of motility rate less than 20%, fertilization rate was 33% (43/130) and pregnant rate was 19% (4/21). We also considered the sperm concentration after the swim up cases. In the cases sperm concentration less than 1 × 10 6/ml, fertilization rate was only 2.3% (2/86) or no cases got pregnant (0/13). We could not found definite correlation between female ages or quantity of picked up oocyte and rate of fertilization and pregnancy respectively. It mentioned that these factors are not applied to the indication of primary ICSI. We concluded that the indication of primary ICSI should be based on the sperm concentration and the numerical numbers were less than 10 × 10 6/ml for ordinary cases and less than 1 × 10 6/ml for after the swim up cases.
