Abstract
Objectives: To identify preoperative risk factors for development of postoperative cerebral hyperperfusion syndrome (CHS).
Methods: 103 consecutive patients that underwent a revascularization procedure (CAS, n=52; CEA, n=51) from January 1998 to October 2006 in our department were analyzed.
Results: The incidence of CHS was 6.8%. On multivariate analysis, Type III cerebral blood flow (CBF) in the middle cerebral artery (MCA) territory and crescendo transient ischemic attacks/ fluctuating minor stroke (cTIAs/ fMS) were significant risk factors for postoperative CHS. The incidence of CHS was 0% in cases with no risk factors (Grade 0), 15% in cases with one risk factor (Grade I), and 80% in cases with two risk factors (Grade II); with a statistically significant difference in incidence of CHS between grades.
Conclusion: These findings suggest that type III CBF in the MCA territory and cTIAs /fMS are risk factors for postoperative CHS. The incidence of CHS increases according to the number of risk factors.