2023 Volume 72 Issue 4 Pages 337-343
With the introduction of Japan's specific health examination (hereafter referred to as ‘health checkup’), the standardization of blood biochemistry tests at each facility was promoted.
The Association for Preventive Medicine of Japan (hereinafter referred to as the ‘Association’) conducts health examinations throughout Japan as an occupational health registration organization and has received Privacy Mark certification. This time, we analyzed AST, ALT, γ-GT, total cholesterol (T-CHO), triglyceride (TG), HDL-cholesterol (HDL-C), LDL-cholesterol (LDL-C), Blood sugar (GLU), hemoglobin A1c (HbA1c, NGSP (international standard) value), and creatinine (CRE) and uric acid (UA), which are often performed at the same time as a legal medical examination, and BMI (Body Mass Index) as an index of the overall condition of the body from 2008 to2017.
First, we calculated individual variation for the five years from 2008 to 2012 as one segment. The calculation results were verified by comparing them with individual variation ranges calculated for five groups, starting from 2009 to 2013.
As a result, there was no difference between each group and the reference year (2008 study start group) (p>0.05), so the initial calculated value was determined as a representative individual variation. This value was obtained from healthy subjects, and its application is limited to individuals showing test values within the reference range. It is speculated that it can be applied to early improvement guidance for health conditions, such as when the numerical value rises beyond the individual variation.
In the future, it is expected that it can be used as an indicator for changes in health checkup values for each individual.
