Investigation of the side effect in the administration of saireito for the chronic subdural hematoma

Abstract

We investigated the side effects of saireito in patients who had received it for prevention of the recurrence of chronic subdural hematoma. The subjects were 561 patients who had undergone surgery for chronic subdural hematoma at 3 centers. Seventy-two patients received saireito, and five (6.9%) of them experi­enced the side effects: 2 patients had interstitial pneumonia, one with liver dysfunction, hypokalemia and cramps calf. We need to be careful of these side effects when administering saireito for prevention of the recurrence of chronic subdural hematoma.