Experience of keishibukuryogan in the acute-phase of intracerebral hemorrhage

Abstract

In Japanese traditional medicine, intracerebral hemorrhage (ICH) caused by intraparench­ymal bleeding can be recognized as “oketsu” syndrome, or so-called blood stasis syndrome. We treated nine patients with acute-phase ICH with keishibukuryogan (2.5 g three times a day before each meal), a formulation from the kuoketsu drug group. Of the patients treated with keishibukuryogan, two patients showed early improvement of cerebral edema, early hematoma absorp­tion, and corresponding improvement of neurologic symptoms. We did not discuss the usefulness of keishibukuryogan in this paper, as the number of cases was small. More cases of ICH treated with keishibukuryogan must be accumulated, and appropriate studies must be conducted to evaluate its usefulness.