2017 Volume 3 Issue 1 Pages 48-53
We investigated the effect of postoperative administration of goreisan to prevent recurrence in patients who underwent surgery for chronic subdural hematoma (CSDH) and their clinical characteristics. The 384 CSDHs in 279 patients were divided into three groups: 302 CSDHs who underwent burr hole irrigation surgery without postoperative administration of goreisan (no administration group), 51 in whom treatment with goreisan was initiated between postoperative days 0 and 10 (early administration group), and 31 in whom it was administered between postoperative days 11 and 56 (late administration group).
Goreisan tended to be administered to patients who had a high risk of recurrence, such as high density, high volume, and high residual volume hematoma. Recurrence rate was 11.7% (45 ⁄ 384 CSDHs) overall, 11.3% (34 ⁄ 302) in the no administration group, 19.6% (10 ⁄ 51) in the early administration group, and 3.2% (1 ⁄ 31) in the late administration group. There was no significant difference in the recurrence rate between these three groups. However, the recurrence rate in the late administration group tended to be lower than that in the early group.
In high-recurrence-risk patients, no effect of goreisan in preventing CSDH recurrence postoperatively was observed in this study. However, in the patients in whom the risk of recurrence was deemed not high just after surgery, goreisan administration may be indicated.
