Effective Kampo medicine treatment for suspected radiation necrosis after repeated stereotactic radiotherapy against metastatic brain tumor: 2 case reports

Abstract

We have experienced 2 cases in each of which enlarging gadolinium–enhanced region after repeated gamma knife radiotherapy decreased its size after intro­duction of goreisan. Each of the regions was assumed as radiation necrosis, and it is not deniable about the effect of steroids or other drug used at the same time, but goreisan probably exerted the effect for treatment of radiation necrosis.