Effectiveness of chotosan in the patients with persistent headache attributed to past stroke: report of three cases

Abstract

Post–stroke headache may persist for a prolonged period and is often difficult to treat. Moreover, post–stoke headache influences the functional outcome and quality of life. The efficacy of Japanese Kampo medicines for chronic headache has recently been reported. We encountered 3 patients diagnosed with persistent headache attributed to past non–traumatic intracranial hemorrhage in whom the symptoms were improved by chotosan (7.5 g/day). Headache was improved by 12 weeks in all 3 patients and disappeared in 2 of the patients. These findings suggest that chotosan should be considered for this condition.