A case report: Brain edema caused by PRES treated with goreisan

Abstract

PRES is caused by endothelial injury related to endogenous ⁄ exogenous factors, which leads to breakdown of the blood–brain barrier and subsequent brain edema, however the patho­physiological changes underlying PRES are not fully understood. Goreisan maintaines bodily fluids as risui drug and there are some reports that goreisan can improve brain edema. We report a patient with PRES due to lumbar puncture and following cerebrospinal fluid hypovolemia in whom brain edema improved following administration of goreisan.