Abstract
Since the seventies, gram-negative bacilli, especially, Pseudomonas, have become increasingly responsible for causing infectious diseases. In most cases, the infection due to Pseudomonas falls under the category of mixed infection, in as much as not only Pseudomonas, but also intestinal flora, above all E.Coli, is responsible as the causative agent. Consequently, in addition to the conventional bacteriological approach, i. e., the studies of the given species of bacillus in isolation, the so-called clinico-bacteriological approach, i. e., the studies of interactions between different species of bacilli, must be taken into consideration. The present study was undertaken to clarify Pseudomonas infection by observing the growth of Pseudomonas under altered environmental conditions. The following results were obtained.
1) Under aerobic conditions, changes in the environments such as the existence of other species of bacilli, changes in pH and the presence of glucoid or bile acids did not affect the growth of Pseudomonas.
2) Under anaerobic conditions, the existence of E. Coli restricted the growth of Pseudomonas, provided that glucoid was added.
