Abstract
It is clinically recognized that the operative therapy of the lumber intervertebral disc herniation offer one of the promising procedures. However, it has also been encountered not uncommonly that some of the cases who had had operative procedure complain post-operative symptomes.
This could be explained on basis of the excessive scar formation in epidural region and adjacent region of the nerve root which may cause irritation of the nerve clinically. This investigation is undertaken to evaluate the versatility of the free adiposal tissue transplantation in the extradural space to prevent the excessive scar formation which may take place post-operatively from the experimental and clinical point of view.
1) Adult rabbits were served as materials. The adiposal tissues were excised from the subcutaneous tissue of the back and neck as well as the greater omentum and the tissue was transplanted in the epidural space of the rabbits which underwent the laminectomy. The experimental animals were sacrified chronologically at 1, 3 and 6 months after an operation and the appropriate sections were taken and submitted for conventional light microscopic observation. Even after 6 months after laminectomy, the transplanted adiposal tissues were retained at the site of laminectomy and obviously inhibiting the causation of the adhesion of the dura and adjacent tissue.
2) Clinical observation was made on 53 cases of lumber intervertebral disc herniation who had the surgical treatment. Thirty eight cases in 53 cases had fat tissue transplants and 15 cases had not fat tissue transplants. A comparison was made between above-mentioned two groups and the former disclosed. approximately 24% improvement in SLR test comparing to the latter group. The result may indicate that the adiposal tissue transplantation procedure may prevent the causation of the excessive scar formation which eventually may offer favourable improvement post-operatively.
