Abstract
Coexisted peripheral vascular disease (PVD: ankle/brachial pressure index ARBI<0.75) or carotid artery disease (CTD: Brochenbrough's supraorbita) Doppler flow analysis were diagnosed by non-invasive testings, and correlated with clinical pictures and coronary backgrounds in 121 consective patients with confirmed coronary artery disease. PVD were found in 16.5%, CTD in 33.1% and both PVD and CTD in 9.9%. The mean age of PVD (+) patients was significantly higher than that of PVD (-) patients, furthermore CTD (+) patients displayed a significantly larger number of coronary risk factors than CTD (-) patients. Concerning the subjective symptoms, 20% of PVD (+) patients and 45% of CTD (+) patients were asymptomatic regarding PVD or CTD symptoms. However the degree of calcification of the aortic arch on the chest X-film (n=-104) significantly cor-related with A/BPI. In patients with AMI, PVD patients showed significantly higher peak CK and CK-MB values than those in PVD (-) patients, which suggested large infarct size in coexistent PVD patients. With respect to the relationship between coronary risk factors, there was a statistically significant difference between PVD (+) patients and PVD (-) patients in terms of the obesity ratio in males as well as hypercholesterolemia ratio and obesity ratio in females. In CTD patients, significant differences between CTD (+) and CTD (-) patients were found with respect to the smoking ratio and obesity ratio in males as well as the smoking ratio in females. In whole study patients. A/BPI with lowered and A.I. (atherogenic index) increased significantly when patients possessed coronary risk factors equal or more than 4 items, which suggested the progression of PVD with incureasing number of coronary risk factors. Key words: coronary artery disease, peripheral vascular disease, acute myocardial infarction, coronary risk factors.
