Abstract
The use of radioisotopes and radiation is essential in the research field of life science. This article describes the studies on the usefulness of radioisotope in pharmaceutical sciences, especially focusing on the results of our research group as follows. (i) Mixed disulfide formation catalyzed by Cu (II) in relation to the radioprotective ability of a radioprotector, cysteamine (2-mercaptoethylamine). (ii) Suppression of reactive oxygen species (ROS) in the skin of live animals given oral administrations of Zn (II) and its complexes in relation to the skin damage under ultra-violet (UV) light. (iii) Improvement of diabetes mellitus by insulin-mimetic vanadyl (IV) (VO (II) ) complexes.
