Abstract
We observed the influences of dietary protein and amino acid compositions on hepatic CoA contents of young albino rats.
By low protein diet feeding, the body weight, liver weight and hepatic hitrogen content were all lower than in the standard diet group, and the total hepatic CoA was remarkably reduced.
CoA per unit of liver weight was higher in the standard diet group during the first one to two weeks of feeding, and the amount of CoA per unit of hepatic weight or nitrogen content was increased in the low protein diet group as the days of feeding elapsed.
Methionine, lysine, threonine or tryptophan deficient group did not show any difference in the gain of body weight but the amount of hepatic CoA was greatly reduced in methionine deficiency, slightly decreased in lysine and tryptophan deficiencies and unaltered in threonine deficiency.
