Effect of Retinol Feeding on Liver Cholesterol of Rats

Abstract

Feeding of 14, 400, 28, 800, 57, 600 and 93, 600 I. U. of retinol respectively to adult rats significantly raised their hepatic vitamin A and esterified cholesterol contents as compared to control rats. The incorporation of acetate-1-¹⁴C radioactivity into hepatic total cholesterol was significantly increased in rats fed 93, 600 I. U. of retinol as compared to control. Incorporation of acetate-1-¹⁴C radioactivity was significantly higher in hepatic free cholesterol of all the retinol fed groups as compared to control.