EFFECT OF COBALT-PORPHYRIN ON THE GROWTH OF VITAMIN B₁₂-PRODUCING MICROBES

Abstract

1. The possibility of the importance of cobalt-porphyrin on the growth of vitamin B₁₂-producing strains was suggested by the observations of a marked and constant increase in Streptomyces olivaceus PD 61, goat-gastric Infusoria and Actinomycetes in cows on chlorophyll-containing ration.
2. The biosynthesis of vitamin B₁₂ by vitamin B₁₂-forming organisms seems to be concerned with cobalt-porphyrin rather than 5, 6-dimethylbenzimidazole.