Abstract
1. A synergistic action of vitamin E for insulin with respect to glucose uptake and glycogen synthesis has been demonstrated in diaphragm from protein-depleted rats.
2. Vitamin E added as a dietary supplement brings about increases in pyruvic acid accumulated during incubation of the diaphragm, but no synergistic action for insulin in this respect was found.
3. The findings are discussed, and it is suggested that the action of vitamin E invo ves the synthesis of ATP.