Abstract
Thioctic acid was determined microbiologically using Streptococcus faecalis 10 C1. The serum level of thioctic acid was frequently found to be reduced in patients with diseases of the liver, especially in those with liver cirrhosis. In patients with severe diabetes mellitus and in some patients with polyneuritis or arteriosclerosis, the serum level of thioctic acid was also found to be decreased.
