EFFECTS OF PYRIDOXAL PHOSPHATE ON BLOOD COAGULATION AND FIBRINOLYTIC SYSTEM

Abstract

1. At high concentrations, pyridoxal phosphate inhibited the blood coagulation both in vivo and in vitro. This inhibitory action is not physiological.
2. At very low concentrations, pyridoxal phosphate activated the fibrinolytic activity both in vitro and in vivo.
3. It was demonstrated from the absorption spectra that ε-aminocaproic acid combined with pyridoxal phosphate in vitro.