Abstract
Although options of drugs for the treatment of acne vulgaris have increased in recent years, particularly those of topical drugs, sometimes a continuing process of trial and error is required to select drugs while taking account of various characteristics of patients. Therefore, we formed a consensus on the selection of drugs for initial treatment in representative patients with acne vulgaris that physicians see in routine clinical practice, and published the results as a first report in this journal. In the current study, we performed the following remaining tasks: We prepared a proposal for the selection of drugs for cases in which the effect of initial treatment was insufficient or in which adverse reactions occurred in initial treatment, and formed a consensus among physicians who are expert at treating acne based on a questionnaire survey and through discussion. Here, we report the results of review of treatment options for 4 representative patients with moderate disease for whom the effect of initial treatment was insufficient, and for patients who had adverse reactions in initial treatment containing adapalene or benzoyl peroxide. We hope that this consensus, combined with the previously reported consensus on the selection of drugs for initial treatment, will be helpful in daily clinical practice.
