Evaluation of the efficacy of combinations of second-generation antihistamines in pruritus based on shared decision making

Abstract

Second-generation antihistamines play an important role in treatment for pruritus. However, there are no clinical data on the efficacy of combinations of second-generation antihistamines. Although the importance of shared decision making (SDM) has been recognized in recent years, there are also no data on choices of antihistamines/antihistamine combinations arrived at through SDM. In this study, we examined chronic urticaria patients treated with combinations of second-generation antihistamines using SDM in the choices for treatment. We report on the selected combinations in terms of efficacy and safety.