Studies on the trichloroethylene metabolism and storage of urinary trichloroethylene metabolites

Part 2. Organ distribution of trichloroethylene in the mice after exposure to trichloroethylene

Abstract

The organ distribution and the concentration of trichloroethylene were defermined in mice exposed to trichloroethylene 500ppm.
Organ distribution of trichloroethylene was in the descending order of adipose tissue, such as the kidneys, the lung, the liver, the spleen, the heart, the digestiveorgan and brain. The concentration of trichloroethylene in the organ decreased in descending order of the blood>the kidneys>the brain>the heart. Biological half lif in the blood, the lungs and the kidney was within 30 minutes and that in the brain, the stomach and the heart over 2 hours.