Discrepancies between pathological examination and imaging analysis after primary systemic chemotherapy for breast cancer: report of two cases

Abstract

Primary systemic chemotherapy (PSC) in breast cancer prolongs disease-free survival in patients who have obtained pathological complete remission (pCR).In combination with pathological examination, CT and MRI have been used to evaluate the efficacy of PSC, they generally coincide well with pathological evaluation.We here present two cases showing discrepancies between pathological examination and imaging analysis after PSC in breast cancer.We should keep such discrepancies in mind to determine the ideal treatment after PSC.An accurate method of evaluating cellular damage by PSC is needed.