Studies on Respiration and Glycolysis of Bone Marrow

Part 3. Study on the Relations of the so-called Banti's Disease and Respiration and Glycolysis of Bone Marrow

Abstract

1. The respiration and glycolysis action of sternal punctate of the so-calld Banti's disease patients has shown the increasing value with the increase of the immatured erythroblast count in their bone marrow picture, but it has come to show the normal condition value or decreased respiration value by splenectomy.
2. The sera of this patients inhibited directly oxygen consumption of the slices of normal rabbit's bone marrow. The serum of the splenectomised patient showed the nealy same value as was the normal person serum, or on the contrary showed the increasing value.
3. Spleen extracts of patients who have had hematologic changes in his life time had no effect upon the respiration and glycolysis action of normal rabbit bone marrow. But in the case of rabbits injected with the spleen extract of the so-called Banti's disease patient, it was shown strikingly that both respiration and glycolysis had in increased of greatly. And in the case of the rabbits injected with the serum of the Banti's disease patient, it was proved that the increase of the respiration action of bone marrow was markedly promoted.