Okayama Igakkai Zasshi (Journal of Okayama Medical Association)
Online ISSN : 1882-4528
Print ISSN : 0030-1558
The Fate of Parathion in vivo
Tatsuji NAMBAHajime TANIMOTOKiichiro KIMURAArimitsu FUKUHARAMinoru YAMADATakeshi NAKAZAWATetsuzo SHIROMOTO
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1956 Volume 68 Issue 8 Pages 1207-1209

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Abstract
Parathion is distributed equally in the poisoned human bodies, as it has been in the case of experimental animals, and disappeared after 24-48 hours. This may be attributed to the splitting of parathion both p-nitrophenol and diethyl (thio) phosphate.
The most part of p-nitrophenol is excreted in the urin within 1-2 days and only a part of it prolonged into a week accompaniing no sign of poisoning.
It is said that diethyl (thio) phosphate is excreted similary, but poisonus (1/4-1/5 of parathion) for the human bodies and animals. The splitting above mentioned is based on the enzym action, including cholinesterase which is found in the animal sera and organ extracts. The parathion splitting action of serum is inhibited in the case of various kinds of disease.
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© Okayama Medical Association
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