Abstract
The author studied the influences of the storage conditions on the immunogenicity of the vaccine of Rickettsia tsutsugamushi. The formol vaccine was prepared from the ascites of the guinea-pigs previously injected with chlorpromazine and then intraperitoneally inoculated with R. tsutsugamushi. The results are summarized as follows:
1) By the storage at 4°C, the immunogenicity of vaccine is well preserved for about 1 year. After 1.5 year, however, it is markedly diminished.
2) By the storage at room temperature, 15 to 25°C, the immunogenicity of vaccine becomes very unstable and is markely diminished after 3 months.
