Okayama Igakkai Zasshi (Journal of Okayama Medical Association)
Online ISSN : 1882-4528
Print ISSN : 0030-1558
An experimental study on the influences of prophylactic irradiation of X-ray upon the lymphatic metastasis of cancer
Part III. An experimental study on growth and proliferation of cancer in the X-ray irradiated lymphnodes
Yasunori Kuwada
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1959 Volume 71 Issue 3-1 Pages 817-831

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Abstract
The growth of cancer cells in the lymphnodes was studied in two groups; one group after 24 hours from X-ray irradiation and the other after 4 weeks from X-ray irradiation. The growth of tumor and its reciprocity between surrounding connective tissue, capsule and tabecle of lymphnodes were also studied. Furthermore fibrisation of lymphnodes 4weeks after X-ray radiation and proliferation of capsule and connective tissue of parenchym were studied.
1) In case of injection after 24hours from irradiation the growth of tumor in the irradiated lymphnodes was better in those irradiated 5 times every day with 300 r or 600 r once than in those irradiated with 60 r or non-irradiated.
2) In case of injection after 4 weeks from irradiation with 300 r 10 times every other day the growth was less than the non-irradiated group.
3) Between the growth of tumor in lymphnodes and the increase of capsule and trabecle there was generally an inverse relation. The more the tumor is, the less the thickness of capsule and connective tissue of trabecle.
4) The capsule and trabecle of lymphnodes irradiated with X-ray are factors influencing on the growth of tumor. In the early stage after irradiation the anti-cancerous power of capsule and trabecle of lymphnodes was weakened, but after 4 weeks from irradiation it was accelarated.
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