Abstract
In an attempt to observe the variations of each fraction of serum protein in pregnancy, the serum of 6 pregnant women was analyzed by the use of paper electrophoresis, serially from the second to the tenth month in the same individual.
In comparing the results obtained from the specimens taken at random from different individuals from the second to the 10th month, the same trend was seen in this series, namely, decrease of plasma protein, ratio of ablumin to globulin and converse increase of α and β-globulin proportional to the advance of gestation and no remarkable change of γ-globulin was observed.
Since the change of distribution of each fraction of serum protein in pregnancy seems to be dependent upon the liver function, increase in consumption of protein in organism, and effect of hormones produced from the placenta, protection of liver function, and ample supply of protein should be an important, effective procedure against toxemia.
