1959 Volume 71 Issue 3supplement-1 Pages 11-18
In the quantitative study on the fluctuations of serum electrolytes in the mice experimentally infected with Japanese B encephalitis virus and in the patients with Japanese B encephalitis, the author obtained the following results:
At the onset of symptoms of Japanese B encephalitis in the test mice and during the period from the progressive stage to the peak of the disease in the patients with Japanese B encephalitis, the quantities of Ca, K, Na, and Cl in the sera are dereased while the contents of inorganic phosphorus are increased. In addition, of the changes in the quantities of these serum electrolytes, inorganic phosphorus alone have increased already in the latent period.
These changes in the serum electrolyte contents seem to be induced by many complex factors nevertheless at least the changes in the functions of the vegetative nervous system and in the nucleic acid metabolisms of various organs, constituting a portion of pathophysiology in this disease, appear to be the important causative factors.
