The determination of urinary metabolites of ethylbenzene in men by high performance liquid chromatography
1984 Volume 96 Issue 5-6 Pages 531-535
Details
1984 Volume 96 Issue 5-6 Pages 531-535
After two volunteers were exposed to 65.0 ppm ethylbenzene for 3 hours, the metabolites of ethylbenzene in their urine, mandelic acid (MA), hippuric acid (HA) and phenylglyoxylic acid (PhGA) were analyzed. The metabolites were excreted in the urine in the order of MA>HA>PhGA. The highest value of excretion of metabolites was observed six to ten hours after the beginning of exposure. MA/PhGA and HA/ PhGA mole ratios of total excretion in urine were 3.5 and 2.6, respectively.
