Abstract
Osteoblasts are distributed in a single layer along the surface of the bone matrix. While several type of osteoblasts are recognized during the process of bone matrix formation, osteoblasts active in the formation of the bone matrix possess extremely well developed rough endoplasmic reticulum and Golgi apparatus and exhibit the morphology of plump typical collagen formed cells. We therefore investigated the organelles of the osteoblasts that possess the ability to actively form the matrix of bone on the basis of the dilute osmium digestion method of Tanaka et al. and a high resolution scanning electron microscope.
