Effects of cerebral white matter lesions and cerebral microbleeds on cognitive dysfunction due to infratentorial lesions

Abstract

To clarify the association between cognitive dysfunction and cerebral white matter lesions and cerebral microbleeds hemorrhage in patients with cerebrovascular disease with infratentorial lesions, patients' medical records of patients admitted to a convalescent rehabilitation ward in a case-control design were used. Associations were revealed between the degree of periventricular lesions and frontal lobe function, and between the degree of deep white matter lesions and frontal lobe function. An association was also found between infratentorial cerebral microbleeds. These findings suggest that cerebral white matter lesions, infratentorial microbleeds, and frontal lobe function are associated with cerebral white matter lesions and infratentorial microbleeds in patients with cerebrovascular disease with infratentorial lesions.