2022 Volume 25 Issue 2 Pages 87-92
Docosahexaenoic acid (DHA), one of omega-3 fatty acids, has been reported to be partially effective for reduction of seizure frequency in human with refractory epilepsy. However, it is unclear whether DHA could be also useful in dogs with idiopathic epilepsy. In this study, the efficacy of additional administration of highdose DHA to the dogs with idiopathic epilepsy was investigated. Here, one case which were treated and observed for 6 months is reported as a case study. A three-year-old male Chihuahua, 2.0 kg BW. While he had multiple antiepileptic drugs, she had 4 seizures and 8 prodromes per month. After DHA was added at 83 mg/kg twice daily, the number of seizures tended to decrease. Consequently, no seizures or prodromes were observed 5 to 6 months after the start of administration. No adverse events were observed during observation period. It is suggested that high-dose of DHA could be effective in improving the frequency of seizures in idiopathic epilepsy of dogs. Accumulation of more cases should help clarify the usefulness of this treatment.
