Journal of Pediatric Cardiology and Cardiac Surgery
Online ISSN : 2433-1783
Print ISSN : 2433-2720
Case Report
Cytokine Storm Originating from the Intrapericardial Cavity in a Child With Pericardial Effusion Following COVID-19
Shusei EbiharaYoshihiko Kodama Kazunari TakamuraMasako HaradaHiroshi Moritake
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JOURNAL OPEN ACCESS

2024 Volume 8 Issue 2 Pages 82-86

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Abstract

Symptoms of coronavirus infectious disease 2019 (COVID-19) are usually mild in young patients. Some children, however, present with a significant degree of complications which may be associated with an excessive reaction by the immune system. Herein, we report an analysis of cytokine and chemokine in an 11-year-old girl diagnosed with left ventricular dysfunction and cardiac tamponade complicated with COVID-19. She recovered without complications after intravenous immunoglobulin, dexamethasone, remdesivir, and surgical pericardial drainage. Cytokine concentrations had markedly increased in the pericardial fluid specimen; especially for interleukin-6 being disproportionate to its serum concentration. Cytokine storm originating from the pericardial cavity was considered an underlying mechanism of her condition.

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© 2024 Japanese Society of Pediatric Cardiology and Cardiac Surgery

This article is licensed under a Creative Commons [Attribution-NonCommercial-NoDerivatives 4.0 International] license.
https://creativecommons.org/licenses/by-nc-nd/4.0/
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