Dataset for proteome analysis of soleus and extensor digitorum longus muscles in mice exposed to hypergravity (3-g)

Abstract

We investigated the effect of hypergravity exposure on the proteome profiles of the slow-twitch soleus and fast-twitch extensor digitorum longus muscles of mice. Mice were raised under 3-g (hypergravity) or 1-g (control) conditions, and proteins extracted from the soleus and extensor digitorum longus muscles were subjected to quantitative proteomic analysis using data-dependent acquisition mass spectrometry (DDA-MS). The proteome profiles of the soleus and extensor digitorum longus muscles suggested that biological pathways in different muscle types responded differently to hypergravity exposure.