Molecular Cloning of Monkey Histamine H4 Receptor

Tamaki Oda; Shun-ichiro Matsumoto; Mitsuyuki Matsumoto; Jun Takasaki; Masazumi Kamohara; Takatoshi Soga; Hideki Hiyama; Masato Kobori; Masao Katoh

doi:10.1254/jphs.SC0050033

Molecular Cloning of Monkey Histamine H₄ Receptor

Tamaki Oda, Shun-ichiro Matsumoto, Mitsuyuki Matsumoto, Jun Takasaki, Masazumi Kamohara, Takatoshi Soga, Hideki Hiyama, Masato Kobori, Masao Katoh

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Keywords: histamine, H₄ receptor, G-protein coupled receptor

JOURNAL FREE ACCESS Advance online publication

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DOI https://doi.org/10.1254/jphs.SC0050033

The final version of this article is now available: Vol. 98 (2005) , No. 3 p.319

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Abstract

Histamine H₄ receptor is considered as a novel therapeutic target for allergic diseases. To enhance the knowledge about species difference, which is essential for drug discovery research, monkey H₄ receptor was identified. Monkey H₄ receptor was characterized to have comparable similarity with its human counterpart. Discovery of monkey H₄ receptor will contribute to a better interpretation of effective drug discovery.

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