The Japanese Journal of Pharmacology
Online ISSN : 1347-3506
Print ISSN : 0021-5198
ISSN-L : 0021-5198
EFFECT OF MONOAMINE OXIDASE INHIBITOR ON DEVELOPMENTAL MECHANISM IN THE AMPHIBIAN
HIDEYO OSHIKAKENGO NAKAI
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1965 Volume 15 Issue 1 Pages 82-87

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Abstract
Accumulating evidence indicates that monoamine oxidase (MAO, 1.4.3.4) is essential to the metabolism of serotonin and catecholamines. Since these amines are substances of high biological activity and have been implicated in autonomic function, it becomes of great interest to see whether foetal or embryonic development is closely related to the metabolism of these biogenic amines.
Therefore, evaluation of action of MAO inhibitor on animals in undeveloped stage may afford some clue as to the biological significance of the amines.
The present paper deals with appearance of MAO in the larval stage of the amphibian and also with effect of MAO inhibitor on the developmental mechanism.
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© The Japanese PharmacologicalSociety
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