Abstract
Succinylcholine is a non-competitive blocking agent with both depolarizing and desensitizing actions. The drug produces a contracture in avian (1) and mammalian (2) muscles containing slow fibres. Katz and Eakins (2) have suggested that succinylcholine produces excitation of the slow fibres and depression of the fast fibres. The present study was undertaken to clarify the mechanism of the succinylcholine contracture of frog slow muscle fibres.
