Abstract
In an investigation of the pharmacological activities of a large number of substituted diaminopyridine and the corresponding imidazo- and triazolo pyridines it was found that imidazo- and triazolo (c) pyridines, in general, produced central depressant action and amongst these 1-(β-phenylethyl) triazolo (4, 5-c) pyridine hydrochloride (PCA9) showed relatively better sedative and tranquillizing effects in mice (1, 2). In view of the tranquillizing activity of PCA9 a study on some neuro-psychopharmacological and other pharmacodynamic effects of this compound was carried out to elucidate the pattern of activity and the results of which are embodied in the present communication.
