Abstract
Although noradrenaline (NA) is well known for its pressor effect, it has been shown to produce a depressor response in hypothermic cats and dogs (1, 2) ; the mechanism of the latter effect has, however, not yet been clearly elucidated. This effect has been attributed to its ganglion blocking action (1) as well as to the parasympathetic over-activity resulting from the altered state of the higher autonomic center during hypothermia (2). It was, therefore, the object of this study to investigate further the mechanism of this depressor response to NA during hypothermia.
