The Japanese Journal of Pharmacology
Online ISSN : 1347-3506
Print ISSN : 0021-5198
ISSN-L : 0021-5198
EFFECT OF 2-CHLORO-11 (4'-METHYL) PIPERAZINO -DIBENZO (b, f) (1, 4)-THIAZEPINE ON SOMATIC REFLEXES IN CAT
J.N. SHARMAR.C. SRIMAL
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1969 Volume 19 Issue 2 Pages 268-274

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Abstract
Pharmacological properties of a potent neuroleptic agent, 2-chloro-ll-(4'-methyl) piperazino-dibenzo (b, f) (1, 4)-thiazepine (HF-2159) have been described by Stille et al. (1). Its profile of activity is in between chlorpromazine and haloperidol, both of which have marked effects on somatic reflexes (2-6). The present investigation has been undertaken to study the effect of HF-2159 on the somatic reflexes integrated at the spinal and the supraspinal level. Preliminary results of this study have appeared (7).
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